A PECULIAR CASE OF PNEUMONIA DUE TO MYCOPLASMA PNEUMONIAE IN A CHILD WITH CYSTIC FIBROSIS AND SENSIBILIZATION TO ASPERGILLUS FUMIGATUS

A Peculiar Case of Pneumonia due to Mycoplasma pneumoniae in a Child with Cystic Fibrosis and Sensibilization to Aspergillus fumigatus

Aspergillus fumigatus plays read more a major role in pulmonary exacerbations in patients with cystic fibrosis.The most common A.fumigatus diseases are those based on immune-mediated response to A.fumigatus antigens; including allergic bronchopulmonary aspergillosis (ABPA).In this condition; the presence of A.fumigatus in the lower respiratory trac

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Unveiling ac4C modification pattern: a prospective target for improving the response to immunotherapeutic strategies in melanoma

Abstract Emerging evidence has confirmed the inextricable connection between N4-acetylcytidine (ac4C) mRNA modification and the clinical characteristics of malignancies.Nonetheless, it is uncertain whether and how ac4C mRNA modification patterns affect clinical outcomes in melanoma patients.This research integrated single-cell sequencing data and t

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A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions

Abstract Background The term mesenchymal stromal cells (MSCs) designates an assorted cell population comprised of stem cells, progenitor cells, fibroblasts, and stromal cells.MSCs contribute to the homeostatic maintenance of many organs through paracrine and long-distance signaling.Tissue environment, in both physiological and pathological conditio

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